The Neuron: Cell and Molecular BiologyOxford University Press, 2002 - 603页 The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neuron generates varied patterns of electrical activity. Next are covered the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter and hormones at synaptic junctions between neurons. The second part of the book covers the biochemical pathways that are linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory. New for the Third Edition: This is a thoroughly revised and expanded edition (60 pages longer) and features a new 8-page, 4-color insert as well as the following changes: 1. The mapping of the human genome and that of other species has led to the discovery of numerous new proteins that regulate the excitability, development, and function of neurons. These have been incorporated into the new edition in nearly all of the chapters. 2. The first section of the book, which deals with neuronal excitability, has been reorganized to make it more readable for those students with less background in physical sciences. A new chapter has been added to this section to allow the incorporation of new information on ion channel structure and on the role of channel auxiliary proteins in modulating neuronal excitability. 3. A new chapter, "The Birth and Death of Neurons," has been added to the last section. In addition to covering new discoveries about the early development of neurons, this chapter describes the recent discovery that new neurons are continually being formed in certain parts of the adult mammalian brain. It also describes research on stem cells, which holds therapeutic potential for the repair of damaged or diseased brain tissue. 4. The use of imaging technologies in the study of the brain has expanded enormously in the past few years. The new edition describes some of these new approaches. Moreover, the introduction of full color plates now allows many new images to be presented in their original form. |
在该图书中搜索
共有 96 个结果,这是第 1-5 个
第46页
很抱歉,此页内容受限.
很抱歉,此页内容受限.
第59页
很抱歉,此页内容受限.
很抱歉,此页内容受限.
第60页
很抱歉,此页内容受限.
很抱歉,此页内容受限.
第67页
很抱歉,此页内容受限.
很抱歉,此页内容受限.
第72页
很抱歉,此页内容受限.
很抱歉,此页内容受限.
目录
Signaling in the Brain | 5 |
Form and Function in Cells of the Brain | 25 |
Electrical Properties of Neurons | 45 |
Electrical Signaling in Neurons | 47 |
Membrane Ion Channels and Ion Currents | 67 |
Ion Channels Are Membrane Proteins | 89 |
Ion Channels Membrane Ion Currents and the Action Potential | 113 |
Diversity in the Structure and Function of Ion Channels | 139 |
Receptors and Transduction Mechanisms II Indirectly Coupled ReceptorIon Channel Systems | 285 |
Neuromodulation Mechanisms of Induced Changes in the Electrical Behavior of Nerve Cells | 315 |
Sensory Receptors | 341 |
Behavior and Plasticity | 373 |
The Birth and Death of a Neuron | 375 |
Neuronal Growth and Trophic Factors | 395 |
Adhesion Molecules and Axon Pathfinding | 435 |
Formation Maintenance and Plasticity of Chemical Synapses | 467 |
Intercellular Communication | 163 |
How Neurons Communicate Gap Junctions and Neurosecretion | 165 |
Synaptic Release of Neurotransmitters | 195 |
Neurotransmitters and Neurohormones | 223 |
Receptors and Transduction Mechanisms I Receptors Coupled Directly to Ion Channels | 253 |
Neural Networks and Behavior | 507 |
Learning and Memory | 537 |
571 | |
589 | |
其他版本 - 查看全部
常见术语和短语
acetylcholine receptor action potential amino acids axons behavior binding brain brane Ca2+ calcium channels cDNA cell bodies cellular chan changes channel protein Chapter chemical cloning complex components cyclic AMP cytoplasmic dendrites depolarization domain electrical activity electrical synapses encoding enzyme ephrins example exocytosis extracellular Figure function G protein ganglion genes glutamate gradient growth cone growth factor hair cells hormones hyperpolarization inactivation injection inputs interactions ion channels ligand mechanisms membrane potential messenger RNA modulation molecular molecules motor neurons muscle mutations nerve nervous system neural neurite neuromuscular junction neurotransmitter neurotrophins nicotinic NMDA normal occurs pathway pattern peptide phosphorylation plasma membrane pore postsynaptic cell potassium channels potassium current properties protein kinase region response retina role second messenger sensory neurons sequence serotonin Shaker signaling sodium channels specific spinal cord stimulation structure subunits synaptic vesicles synthesis target tectum tein termed tion transduction transmitter release tyrosine voltage-dependent
热门引用章节
第581页 - K. Palczewski, T. Kumasaka, T. Hori, CA Behnke, H. Motoshima, BA Fox, I.
第578页 - P. Bregestovski, P. Ascher, A. Herbet, and A. Prochiantz. Magnesium gates glutamate-activated channels in mouse central neurones.
第578页 - C. Methfessel, M. Mishina, T. Takahashi, T. Takai, M. Kurasaki, K. Fukuda, and S. Numa. (1985) Role of acetylcholine receptor subunits in gating of the channel.
第584页 - Serafini, T., Kennedy, TE, Galko, MJ, Mirzayan, C., Jessell, TM, and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.
第575页 - JE (1997). Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90, 523-535.