Organic Chemistry

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OUP Oxford, 2012年3月15日 - 1234 頁
8 書評
Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text.

The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before.

Like the first, the second edition is built on three principles:

An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts;

A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered;

An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding.

The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.


SUPPORT MATERIALS

The Companion Website (www.oup.com/uk/orc/bin/9780199270293), available to all adopters of the text, includes:
- 3D Organic Animations: Link to chemtube3d to view interactive 3D animations developed by the author
- Additional Chapters: Four chapters from the first edition that do not appear in the second
- Errata: Corrections to the book since publication
- End-of-Chapter Questions: A range of problems to accompany each chapter
- Figures in PowerPoint: Figures pre-inserted into PowerPoint for use in lectures and handouts
- Problems: Problems to accompany each chapter from the new edition of Organic Chemistry will be posted in the student area of the book's Companion Website throughout the year (April, June, and December 2012)
 

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內容

1 What is organic chemistry?
1
2 Organic structures
15
3 Determining organic structures
43
4 Structure of molecules
80
5 Organic reactions
107
6 Nucleophilic addition to the carbonyl group
125
7 Delocalization and conjugation
141
8 Acidity basicity and pKsuba
163
25 Alkylation of enolates
584
the aldol and Claisen reactions
614
27 Sulfur silicon and phosphorus in organic chemistry
656
28 Retrosynthetic analysis
694
reactions
723
synthesis
757
31 Saturated heterocycles and stereoelectronics
789
32 Stereoselectivity in cyclic molecules
825

9 Using organometallic reagents to make CC bonds
182
10 Nucleophilic substitution at the carbonyl group
197
11 Nucleophilic substitution at CO with loss of carbonyl oxygen
222
12 Equilibria rates and mechanisms
240
Proton nuclear magnetic resonance
269
14 Stereochemistry
302
15 Nucleophilic substitution at saturated carbon
328
16 Conformational analysis
360
17 Elimination reactions
382
18 Review of spectroscopic methods
407
19 Electrophilic addition to alkenes
427
20 Formation and reactions of enols and enolates
449
21 Electrophilic aromatic substitution
471
22 Conjugate addition and nucleophilic aromatic substitution
498
23 Chemoselectivity and protecting groups
528
24 Regioselectivity
562
33 Diastereoselectivity
852
cycloadditions
877
sigmatropic and electrocyclic reactions
909
36 Participation rearrangement and fragmentation
931
37 Radical reactions
970
38 Synthesis and reactions of carbenes
1003
39 Determining reaction mechanisms
1029
40 Organometallic chemistry
1069
41 Asymmetric synthesis
1102
42 Organic chemistry of life
1134
43 Organic chemistry today
1169
Figure acknowledgements
1182
Periodic table of the elements
1184
Index
1187
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關於作者 (2012)


Jonathan Clayden is a Professor of Organic Chemistry at the University of Manchester, where he and his research group work on the construction of molecules with defined shapes - in particular those where control of conformation and limitation of flexibility is important. Jonathan was awarded a BA (Natural Sciences) from Churchill College, Cambridge before completing his PhD with Stuart Warren, also at the University of Cambridge. He has been at the University of Manchester since 1994.


Nick Greeves is the Director of Teaching and Learning in the Department of Chemistry at the University of Liverpool. Nick is a Cambridge graduate, obtaining his PhD there in 1986 for work on the stereoselective Horner-Wittig reaction with Stuart Warren. He then held a Harkness Fellowship at the University of Wisconsin-Madison and at Stanford University, California, and a Research Fellowship at Cambridge University before joining Liverpool in 1989 where he is currently a Senior Lecturer.

Stuart Warren is a former lecturer in the Department of Chemistry at the University of Cambridge and Fellow of Churchill College, Cambridge. A graduate of Trinity College, Cambridge, Stuart completed his PhD at Cambridge with Malcolm Clark before carrying out post-doctoral research at Harvard University. He became a teaching fellow at Churchill College in 1971, and remained a lecturer and researcher at Cambridge until his retirement in 2006.

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