Science of Synthesis: Houben-Weyl Methods of Molecular Transformations, 第 35 卷Ernst Schaumann Thieme, 2000 - 850 頁 Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008. Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.
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... substrate , mixtures of regioisomeric monochlorinated products will be obtained , as well as possible variations of di- or higher - chlorinated products . Therefore alkane chlorination deserves special interest only for substrates with ...
... substrate that has to be opened . Cyclic ethers with alkyl substituents tend to react prefer- entially to give chloro alcohols and their derivatives with the chloride atom at the less- hindered carbon atom . Aryl - substituted substrates ...
... substrate , reaction conditions , and reagents is necessary , as acidic conditions or high temperatures may not be tolerated by certain functional groups in more labile substrates . Acidic or neu- tral conditions are required to achieve ...