Science of Synthesis: Houben-Weyl Methods of Molecular Transformations, 第 35 卷Ernst Schaumann Thieme, 2000 - 850 頁 Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008. Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.
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... affords a - chlorinated O - heterocycles . Alkoxyalkyl radi- cal fragmentation or a - chloro ether hydrolysis is not a major concern in these reac- tions . ( 74.75 Tetrahydrofuran , for instance , provides 2 - chlorotetrahydrofuran ( 14 ...
... affords 2- ( chloromethyl ) - pyridine ( 24 ) ( Scheme 13 ) . Furthermore , polymethylpyridines ( 2,3 - lutidine , 2,6 - lutidine , and 2,4,6 - collidine ) react with the reagent to give ( chloromethyl ) pyridines . The reaction of 2 ...
... affords benzyl chloride in 76 % yield . ( 28 ) The chloromethylation of 1,3,5 - trimethyl- benzene with a 37 % formaldehyde solution leads to 2- ( chloromethyl ) -1,3,5 - trimethylben- zene ( 55–66 % ) , ( 29 ) 1,2,3,4 ...